Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients

Authors

Maged El-din, Radiation Protection Department, Egyptian Nuclear and Radiological Regulatory Authority, Cairo, Egypt.Follow
Amr Kany, Faculty of science Al-Azhar University, Cairo, Egypt.Follow
Eman Massoud, Jeddah International College, Jeddah, Saudi Arabia.Follow
Ahmed El-Agamawi, Faculty of medicine Al-Azhar University, Cairo, Egypt.Follow
Mohamed Ezz El-din, Radiation Protection Department, Egyptian Nuclear and Radiological Regulatory Authority, Cairo, Egypt.Follow

Corresponding Author

El-din, Maged

Document Type

Original Article

Subject Areas

Mathematics, Statistics, Computer Science, Physics and Astronomy

Keywords

Radioiodine-131; Internal dosimetry; Monte Carlo; Well Differentiated Thyroid Cancer

Abstract

During radiotheranostic procedures, radioiodine-131(131I)activities deliver high internal gamma (ɣ) doses to the patient’s organs. Thus, studying the internaldoses of patients is highly required to predict the stochastic or deterministiceffect of gamma radiation that may occur to patients.The objective ofthis study is to calculatethe internal doses for 11 critical organs or body tissues insideWell Differentiated Thyroid Cancer (WDTC) patients’ bodiesafter receiving diagnostic and therapeutic 131I activitiesorally during 6days post administration.Internal effective doses delivered tocritical organs are estimated mathematically using Monte Carlo simulation model in which the actual geometry, volume, mass of organs and the source localization wasdesigned based onthe patients’ CT images and Oak Ridge National Laboratory (ORNL) phantom.Thus, an average sized human phantom was constructed using MCNP5in whichtwo 131I sources were distributed in the abdominal and the thyroid gland sections.No significant radiation effect is expected during diagnostic procedures for the investigated organs including the thyroid itself. However,some deterministic effects or induction of thyroid cancer might be observedfor patients undergoing postoperative radiotherapy with largeprescribed activities.

How to Cite This Article

El-din, Maged; Kany, Amr; Massoud, Eman; El-Agamawi, Ahmed; and Ezz El-din, Mohamed (2021) "Monte carlo method estimates for internal dosimetry of well differentiated thyroid cancer patients," Al-Azhar Bulletin of Science: Vol. 32: Iss. 2, Article 8.
DOI: https://doi.org/10.21608/absb.2021.93331.1133