Pyridinyldiazenylnaphthols; cationic azo dyes; antimicrobial activity
((E)-4-(pyridin-3-yldiazenyl)naphthalen-1-ol) and (4-((E)–pyridin-3-yldiazenyl)– 8-((Z)-pyridin-3yldiazenyl)naphthalene-1,5-diol) (IIIa, b) were prepared. Condensation of (IIIa, b) with 2-(pyridin-4ylmethylene) malononitrile (V) under Michael reaction conditions gave the corresponding bezo[h]chromene and dihydrochromene[8,7-h] chromene derivatives (VIa, b). The cationic derivatives for (IIIa, b) and (VIa, b) were obtained by quaternization as (IVa,b) and (VIIa,b). The structures obtained were confirmed form IR, 1HNMR and mass spectra studies. The antimicrobial activities were also studied and have been found that; the cationic dyes (IVa,b) and (VIIa) exhibit promising results against Candida albicans.
How to Cite This Article
Hammam, Ahmed; El-Tabei, A.; Hegazy, M.; Mohamed, Mahmoud; and Sadeq, M.
"THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS,"
Al-Azhar Bulletin of Science: Vol. 30:
2, Article 7.