Document Type
Original Article
Subject Areas
Botany, Microbiology and Zoology
Keywords
olive oil; Ficus carica; γ-radiation; histology; cytology
Abstract
The present study was designed to determine the possible protective and therapeutic effects of olive oil and/or Ficus carica against radiation-induced cytological and histological changes in liver and Kidney of male albino rats. Irradiation was performed by whole-body exposure of rats to an acute single dose gamma radiation of 6 Gy. Irradiated rats received, via gavage, extra virgin olive oil (7.6 ml/kg b.wt), and/or extract of Ficus carica fruit (1 g/kg b.wt) before and/or after radiation exposure. Six rats were sacrificed on the 1st and 15th-day post-irradiation exposure at the control and treated irradiated subgroups. Time duration for this experiment was one month.The γ-Irradiation treated group revealedhisto pathological alterations in the hepatic and renal tissues on the 1st and 15th-day post-irradiation as compared to the control rats. The administration of the olive oil and/or Ficus carica showed beneficial results against the deleterious effects of γ-irradiation. A better ameliorative effect was noticed with the combined treatments that revealed the synergistic effect between them.In conclusion, the administration of the olive oil and/or Ficus carica provides considerable radioprotective and radiotherapeutic effects against whole body γ-radiation in male Wistar albino rats.
How to Cite This Article
Gafar, Ahmed; Khalifa, Mahmoud; and Elshaer, Fathy
(2018)
"PROTECTIVE AND THERAPEUTIC EFFECTS OF OLIVE OIL AND FICUSCARICA ON THEHISTOLOGICAL ANDCYTOLOGICAL INJURIESOF LIVER AND KIDNEY IN -IRRADIATED MALE ALBINO RATS,"
Al-Azhar Bulletin of Science: Vol. 29:
Iss.
2, Article 39.
DOI: https://doi.org/10.21608/absb.2018.33820