Corresponding Author

Elhaw, Mohamed

Document Type

Original Article

Subject Areas

Botany, Microbiology and Zoology


Chemical composition; Phytochemical; Galium sinaicum; hypoglycemic agent; LD50


This research aims to evaluate some of the physiological and biochemical aspects of Galium sinaicum plant. Water content, total ash, organic matter, acid soluble and insoluble ash, water soluble and insoluble ash, crude fiber, total carbohydrates, soluble and insoluble carbohydrates, total nitrogen, total protein, total lipids, free amino acids, total phenolics, total flavonoids, total saponins, total tannins and total alkaloids were analyzed in shoots of the tested plant. Preliminary phytochemical screening of Galium sinaicum showed that presence of alkaloid, glycosides , cardiac glycosides, saponins, phenos, phytosterols, tannins, flavonoids , amino acids , while volatile oil is absent. The most of predominant free amino acids in Galium shoots were detrmined and recorded different variations. Lethal Dose (LD50) of methanol extract 70% of Galium sinaicum was 4500 mg /Kg. two specific dose (225 mg/kg and 450 mg/kg) used as hypoglycemic agent of Galium sinaicum, evaluation and results showed that the total extract of Galium sinaicum plant produced high effect as hypoglycemic agent.[Elhaw MH, Aldinary MM. Chemical Constituents and Biological Activity of Galium sinaicum , Family Rubiaceae

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