THE PRODUCTION OF ANTIMICROBIAL AGENTS BY WILD & RADIO ACTIVATED ACTINOBACTER SP.

Authors

MAGED AHMED, Botany Deptartment, Faculty of Sciences, Ben Sewef University, Ben Sewef, Egypt.
MEDHAT ABD EL-MOHSEIN, Botany Deptartment, Faculty of Sciences, Ben Sewef University, Ben Sewef, Egypt.
MOSTAFA SALAMA, Botany Deptartment, Faculty of Sciences, Ben Sewef University, Ben Sewef, Egypt.
HUSSEIN EL-KABBANY, Health Radiation Research Department, National Center for Radiation Research and Technology. Atomic Energy Authority, Cairo, Egypt.

Corresponding Author

AHMED, MAGED

Document Type

Original Article

Subject Areas

Botany, Microbiology and Zoology

Keywords

Antimicrobial agents; ACTINOBACTER SP

Abstract

The production of several volatile substances like Geosmin responsible of the characteristic wet earth odor distributed in terrestrial and aquatic ecosystems, especially in soil. Members of this group are produce clinically useful antitumor drugs such as Anthracyclines, Antimetabolites, Arzinophilin, Mitomycins and Vancomycins . DNA cleavage by topoisomerase I or II inhibition , Mitochondria permeabilization inhibition and inhibiting tumor-induced angiogenesis . Isolation , Purification of Actinobacter from different sources and Determination of biological activities ( Antimicrobial / Anti-tumor ) . Optimization of production media ( natural and synthetic) of the promising bioactive compounds ( Antimicrobial / Anti-tumor ). Finally, Determination of the anti-tumor activity of the bioactive compound (s) of Actinobacter against different tumors.

How to Cite This Article

AHMED, MAGED; ABD EL-MOHSEIN, MEDHAT; SALAMA, MOSTAFA; and EL-KABBANY, HUSSEIN (2013) "THE PRODUCTION OF ANTIMICROBIAL AGENTS BY WILD & RADIO ACTIVATED ACTINOBACTER SP.," Al-Azhar Bulletin of Science: Vol. 24: Iss. 2, Article 20.
DOI: https://doi.org/10.21608/absb.2013.6423