SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW COUMARIN, PYRIDINE, 1,2,3-TRIAZOLE, THIAZOLIDINONE, PYRAZOLOTRIAZINE, THIOPHENE AND THIAZOLE DERIVATIVES BEARING CARBONYLHYDRAZONOETHYLPHENYLTOSYLATE MOIETY

Authors

MAHMOUD ABDELALL, Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
SHABAN MOHAMED, Technology Engineering Institute, Tamoh, Giza, Egypt.
AHMED HALAWA, Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
AHMED HASSAN, Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.
MOHAMED ELNASSAG, Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.

Corresponding Author

ABDELALL, MAHMOUD

Document Type

Original Article

Subject Areas

Chemistry

Keywords

yanoacetylhydrazonoethylphenyltosylate; Pyridine; thiazole; Coumarin; THIOPHENE; pyrazolotriazine; thiazolidinone

Abstract

A number of novel coumarin (4), pyridinone (5a,b), thiophenopyridinone (6), 1,2,3-triazole (7), pyrazolotriazine (10), thiazole (11,14a,b,15), thiophene (12), thiazolidinone (20,21,23) derivatives were synthesized via interaction of 4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyltosylate (3) with different nucleophilic reagents. The structures of the newly synthesized compounds were confirmed by elemental analyses IR, 1H-NMR and mass spectral data. All compounds were evaluated for their antimicrobial activities.

How to Cite This Article

ABDELALL, MAHMOUD; MOHAMED, SHABAN; HALAWA, AHMED; HASSAN, AHMED; and ELNASSAG, MOHAMED (2011) "SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW COUMARIN, PYRIDINE, 1,2,3-TRIAZOLE, THIAZOLIDINONE, PYRAZOLOTRIAZINE, THIOPHENE AND THIAZOLE DERIVATIVES BEARING CARBONYLHYDRAZONOETHYLPHENYLTOSYLATE MOIETY," Al-Azhar Bulletin of Science: Vol. 22: Iss. 2, Article 20.
DOI: https://doi.org/10.21608/absb.2011.7025