THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES

Authors

H. THABET, Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt
M. HELAL, Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt
M. SALEM, Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt
A. FARRAG, Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt

Corresponding Author

THABET, H.

Document Type

Original Article

Subject Areas

Chemistry

Keywords

Thiosemicarbazide derivative; 1, 2, 4-triazoles; pyrazole; Thiazoles; tri-azolylthiazolone; Chromenes

Abstract

The reaction of cyanoacetic acid hydrazide with 4-ethoxyphenylisothiocyanate gave the thiosemicarbazide derivative (3). The latter underwent a series of heterocyclization reactions when it reacts with either α-halo compounds, thioglycolic acid, acetylacetone, cinnamonitrile, or o-hydroxy aldehydes

How to Cite This Article

THABET, H.; HELAL, M.; SALEM, M.; and FARRAG, A. (2011) "THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES," Al-Azhar Bulletin of Science: Vol. 22: Iss. 1, Article 12.
DOI: https://doi.org/10.21608/absb.2011.7179