SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NOVEL THIAZOLO[3,2-A]PYRIDINE, PYRANO[2,3-D]THIAZOLE AND PYRANO [2',3':4,5]THIAZOLO[3,2-A]PYRIDINE DERIVATIVES USING N-CYCLOHEXYL-2-CYANOACETAMIDE

Authors

M. HELAL, Faculty of Science, Chemistry Department, Al-Azhar University, Nasr City 11884, Cairo, Egypt
SH. MOHAMED, Technology Engineering institute, Tammoh, Giza.
Y. MOHAMED, Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt.
A. ALI, Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt.
Y. AMMAR, Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt.

Corresponding Author

HELAL, M.

Document Type

Original Article

Subject Areas

Chemistry

Keywords

acidity; Kinetics; Photodegradation; Degradation of direct blue-1 dye; Sulfated zirconia; texturing

Abstract

A novel and efficient method for the synthesis of a new variety of 2-(N-cyclohexyl-2-cyanoacetamide)-2-thiazolin-4-one and its corresponding thiazolo[3,2-a] pyridines and pyrano[2,3-d]thiazoles by the reaction of N-cyclohexyl-2-cyano-acetamide with thioglycolic acid. The synthetic potential of the method is demonstrated and antimicrobial evaluation.

How to Cite This Article

HELAL, M.; MOHAMED, SH.; MOHAMED, Y.; ALI, A.; and AMMAR, Y. (2010) "SYNTHESIS AND ANTIMICROBIAL EVALUATION OF SOME NOVEL THIAZOLO[3,2-A]PYRIDINE, PYRANO[2,3-D]THIAZOLE AND PYRANO [2',3':4,5]THIAZOLO[3,2-A]PYRIDINE DERIVATIVES USING N-CYCLOHEXYL-2-CYANOACETAMIDE," Al-Azhar Bulletin of Science: Vol. 21: Iss. 2, Article 12.
DOI: https://doi.org/10.21608/absb.2010.7372