SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME 3-(AMINO OR ARYLIDINE)-2-PYRIDINYL-4(3H)-QUINAZOLINONE AND SOME OF THEIR COPPER COMPLEXES

Authors

MOHSEN ALY, Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, Egypt
WAHID BASYOUNI, National Research Centre, Dokki, Cairo, Egypt
YAHIA MOHAMED, Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, Egypt
KHAIRY EL-BAYOUKI, National Research Centre, Dokki, Cairo, Egypt
SAMIR ABBAS, National Research Centre, Dokki, Cairo, Egypt

Corresponding Author

ALY, MOHSEN

Document Type

Original Article

Subject Areas

Chemistry

Keywords

4(3H)-Quinazolinones; Copper complexes; Anticonvulsant; analgesic; Antitumor and antimicrobial activities

Abstract

Several 4(3H)-quinazolinones containing pyridine moiety were synthesized starting from substituted anthranilic acid derivatives. Copper complexes of 3-amino-2-pyridinyl-4(3H)-quinazolinones and some of their derivatives were synthesized and characterized. The synthesized compounds were screened for their anticonvulsant, analgesic, antitumor, as well as, their antimicrobial activities.

How to Cite This Article

ALY, MOHSEN; BASYOUNI, WAHID; MOHAMED, YAHIA; EL-BAYOUKI, KHAIRY; and ABBAS, SAMIR (2010) "SYNTHESIS AND BIOLOGICAL ACTIVITIES OF SOME 3-(AMINO OR ARYLIDINE)-2-PYRIDINYL-4(3H)-QUINAZOLINONE AND SOME OF THEIR COPPER COMPLEXES," Al-Azhar Bulletin of Science: Vol. 21: Iss. 1, Article 1.
DOI: https://doi.org/10.21608/absb.2010.7333