STUDY ON THIAZOLOPYRIDINES PART (7) : SYNTHESIS OF NOVEL THIAZOLIDINONE AND THIAZOLO[3,2-A]PYRIDINE DERIVATIVES

Authors

GAMEEL ELHAG ALI, Department of Chemistry, Faculty of science, Al-Azhar University, Cairo, Egypt
HESSEN ALTAMAMY, Department of Chemistry, Faculty of science, Sebha University, Sebha, Libya
SHAABAN MOHAMED, Technology Engineering Institute, Tamooh , Giza
ZAMZAM BASHER, Department of Chemistry, Faculty of science, Sebha University, Sebha, Libya

Corresponding Author

ELHAG ALI, GAMEEL

Document Type

Original Article

Subject Areas

Chemistry

Keywords

THIAZOLOPYRIDINES, PYRIDINE DERIVATIVES

Abstract

A novel 2-ethoxycarbonyl methylidine-4,5-dihydo-4-oxo-5-arylmethylidine-1,3-thiazole derivatives (2a-c) are obtained via the reaction of 4-thiazolinone derivative (1) with different aromatic aldehydes. Cyclization of 4-thiazolidinone derivatives (2a-c) with various α–cyanocinnamonitriles afforded the corresponding thiazolopyridine derivatives (5a-r). Thiazolopyridine derivatives (5a,b ) are refluxed with acetic anhydride, and gave N,N-diacetyl amino derivatives (8a,b).

How to Cite This Article

ELHAG ALI, GAMEEL; ALTAMAMY, HESSEN; MOHAMED, SHAABAN; and BASHER, ZAMZAM (2008) "STUDY ON THIAZOLOPYRIDINES PART (7) : SYNTHESIS OF NOVEL THIAZOLIDINONE AND THIAZOLO[3,2-A]PYRIDINE DERIVATIVES," Al-Azhar Bulletin of Science: Vol. 19: Iss. 2, Article 21.
DOI: https://doi.org/10.21608/absb.2008.10835