SYNTHESIS AND FUNGICIDAL ACTIVITY OF NEW THIAZOLE DERIVATIVES WERE PREPARED FROM 2-BROMO-1-(3,4-DIMETHYLPHENYL)ETHANONE

Authors

MAHMOUD BASHANDY, Chemistry Department Faculty of Science (Boy's), Al-Azhar University Nasr-City Cairo Egypt
MAHMOUD ABDELALL, Chemistry Department Faculty of Science (Boy's), Al-Azhar University Nasr-City Cairo Egypt
AHMED EL-MORSY, Organic Chemistry Department Faculty of pharmacy (Boy's), Al-Azhar University Nasr-City Egypt

Corresponding Author

BASHANDY, MAHMOUD

Document Type

Original Article

Subject Areas

Chemistry

Keywords

2-bromo-1-phenylethanone; thiazole; 2-aminothiazole; 2-methylthiazole; 2H-chromen-2-one; benzo[b][1, 4]thiazine

Abstract

2-bromo-1-(3,4-dimethylphenyl)ethanone (2) was prepared and converted to thiazole derivatives (6-11a-c, 14-20) through reactions with different reagents. Compounds (3, 5, 12, 13, 21) were prepared from reaction of compound (2) with 2-mercapto-4,6-dimethylnicotinonitrile1H-benzo[d]imidazole-2-thiol, p-chloroaniline, potassium cyanide and 2-aminobenzenethiol respectively. The synthesized compounds were confirmed by elemental analysis, IR, 1H-NMR and mass spectral analysis.

How to Cite This Article

BASHANDY, MAHMOUD; ABDELALL, MAHMOUD; and EL-MORSY, AHMED (2008) "SYNTHESIS AND FUNGICIDAL ACTIVITY OF NEW THIAZOLE DERIVATIVES WERE PREPARED FROM 2-BROMO-1-(3,4-DIMETHYLPHENYL)ETHANONE," Al-Azhar Bulletin of Science: Vol. 19: Iss. 2, Article 18.
DOI: https://doi.org/10.21608/absb.2008.10820