SYNTHESIS OF SOME NOVEL PYRIDINE, THIOPHENE, THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES CONTAINING BENZOFURANYL MOIETY

Authors

J. MICKY, Chemistry Department, Faculty of Science (Girl’s), Al-Azhar University–Nasr City, Cairo, Egypt.
N. SALEH, Chemistry Department, Faculty of Science (Girl’s), Al-Azhar University–Nasr City, Cairo, Egypt.
N. SHEMISS, Chemistry Department, Faculty of Science (Girl’s), Al-Azhar University–Nasr City, Cairo, Egypt.
S. MOHAMED, Chemistry Department, Faculty of Science (Girl’s), Al-Azhar University–Nasr City, Cairo, Egypt.

Corresponding Author

MICKY, J.

Document Type

Original Article

Subject Areas

Botany, Microbiology and Zoology

Keywords

Pyridine; THIOPHENE; THIENOPYRIMIDINE; THIENOPYRIDINE; BENZOFURANYL

Abstract

Interaction of 2-[1-(4,6-dimethoxybenzofuran-5-yl)ethylidine]malononitrile (1) with phenylisocyanate, phenylhydrazine, carbon disulphide and arylidenemalono-nitrile afforded the corresponding pyridine 2, pyrido[2,3-d] pyrimidine 3, phenylhydrazone 4,pyridine 2,6-dithione 8 and benzene dicarbonitrile 9 derivatives . Treatment of 1 with elemental sulfur under Gewald reaction conditions furnished 2-amino-4-(4,6-dimethoxybenzofuran-5-yl)thiophen-3-carbonitrile 11 which used as starting material in the synthesis of thienopyrimidine 14 and thienopyridine 15 derivatives.

How to Cite This Article

MICKY, J.; SALEH, N.; SHEMISS, N.; and MOHAMED, S. (2006) "SYNTHESIS OF SOME NOVEL PYRIDINE, THIOPHENE, THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES CONTAINING BENZOFURANYL MOIETY," Al-Azhar Bulletin of Science: Vol. 17: Iss. 1, Article 9.
DOI: https://doi.org/10.21608/absb.2006.11640